Dosing library

FOXO4-DRI

Cells / mice · No established human dosing schedule

FOXO4-DRI is a senolytic research peptide tested in cells and mice. The published work does not establish a human dose. Cells / mice · No established human dosing schedule.

Reviewed 2026-10-17. A source reference, not a personal treatment plan. Discuss treatment decisions with a qualified clinician.

Dose reference

STUDY CONTEXTDoseFrequencyContext
Human dosingNot establishedNo validated scheduleMouse amounts and spacing cannot establish a human senolytic cycle. There is no validated human administration schedule in the reviewed evidence. Source

Mouse amounts and spacing cannot establish a human senolytic cycle. There is no validated human administration schedule in the reviewed evidence.

Source context

Baar and colleagues investigated disruption of FOXO4–p53 interactions in senescent cells and mouse models. These experiments are not human dose-finding or long-term safety trials.

Reading the dose correctly

Mouse amounts and spacing cannot establish a human senolytic cycle. There is no validated human administration schedule in the reviewed evidence.

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Further reading

FOXO4-DRI monograph on myPeptides

References

  1. Baar et al. (2017) · preclinical senescence study · PMID 28340339

Why is there no numerical dose for FOXO4-DRI on this card?

Mouse amounts and spacing cannot establish a human senolytic cycle. There is no validated human administration schedule in the reviewed evidence.

Does a missing dose mean that no research exists?

This card describes cells / mice. Evidence of a mechanism, a laboratory finding or an exposure does not by itself establish a useful and safe human treatment schedule. The monograph explains the distinction.